???

???180???????1.5???40100??????? ?????????????????????????????????????????????????????
??????????????5%510??????????????? ??????????24??150? ? ?????????????????????????
??????????????????? ??????40??60??100????????????
,????,(??)?(??150 mg),???,??.
?,?,??????.,,?,?????????,????,??.
??,...

?????(??)?(??150 mg)?????????B?????3.5g/24h?
 
(1)???
????????????????????????????(LDL)???(VLDL)?B??A????
(2)????
????????????????????
(3)??
???????????????????????????????PDGFFNMCP-1???
(4)???
??? ?

?? ??????????????????????? ???????????????????????(-)?0.15g/24h??????????????
????
????...

??????????????????
?????100-150mg?150mg???????????negative???10mg/dltrace?10-20 mg/dl1+30 mg/dl???300-400 mg?2+100mg/dl3+(300mg/dl); 4+(?1000mg/dl)
???trace2+???n????????34???24????? ??????????????
1????????????????????
2??????????????????????????????????2?Ccr??????????????????
3???????????????????...

????????i????



????????????200/24?????????200/24???????
??????????????????????????????????????????10g?2g/24h???????????????????????????????2g/24h?1g/24h??????????????????????????????????????????????????????????????????????
??7~10mg/24h???
????B??? ??3.5g/24h?

?????????????????????????????????????????????????????????????????????????
??????????????????
? ?? ?? ??? ?