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?????????3??? ?24??????  ???????? 12 ??????????????????????????2310 ????p???????????? ? ( ?? )????????????????????? (?????????????????????

        
????????(syphilis)??????15??1492????????????????1494????????????1495????1488???????1498??????????????????...

(Syphilis)?????????(Treponema pallidum)???????????????????????????????????????????????????????

??????1493????????40???60?70?10???300?????10--15?1500?1505????????1949???????????48????????1959?????1984--1988?501993????401993?4019941591995?4611996???3521995?76.36???1991?187019921997199320161994459119...