??,??.?,.?????

??:1????????????????????????????????????????
2?
a??????????????????????????^?????
b????????????????
c??????????????????
d??????????????????????????
??????????
e???????D??C???????????????
3??????????????????????? [?]?:(1)???1500ml???????????????
(2)??1??????????????????60g?15g?9g??30g?15g?1??
(3)????...

??????,???????(Fibroblasts),,??,??,???????.?????,????,????,?(Photoaging).???????,,,??,??,????,????.,??,?,??;??????.?,???,????.
??????????????????????????

????????????????

????????

?????????????????

???????????????????????????

??Collagen??????????????????????????????????????33%?H??????????

...

: ??1000?1150??5?


?:??????????????.

?:??,,?????.

:???????(?..??)50K?

?:????,??????????????????????????

:2- 3??! ????1-3???2??????????????

??
??????????????????????????????? ??500???1000?500?500?11?50??5?
?
1?????????????10?
2???????????????
3??????k????????????? 3?
4.????9-10??2...

???
?????????????????????????????????80%99%??90%????????????????????8
?????????????????????????????????????
???
???1?????2?????3?????????????????????
??
?????????35%?????65%??????????????????? ????????????????


??

?

??
????

?
?

??
????????

?



??
???

?
??

?
??


? /?...

???

1?????????????????????????????????????????????????????????????????????????????????????????50????????????????????????????????????
?????????????????????????????????????????????????
2?????????}????????????????????????????????????????????????????????????????????????

???

?????????????????????...